LUPUS BULLOSO PDF

It is a heterogeneous disease that is caused by autoantibodies to the dermoepidermal junction, mainly type VII collagen. Similarities in histology and immunopathology exist between BSLE and other primary bullous dermatoses, namely dermatitis herpetiformis DH and epidermolysis bullosa acquisita EBA , respectively. However, clinical presentation combined with histology, immunological testing, and concomitant diagnosis of SLE distinguish this entity from other similar dermatoses. Diagnosis of this disease is important given its coexistence with SLE and its many complications. In addition, rituximab was recently found to be efficacious in recalcitrant cases of BSLE that do not respond to dapsone and immunosuppressants. We review the topic of BSLE with emphasis on clinical, histologic, and immunopathologic features, as well as new methods of diagnosis and treatment.

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It is a heterogeneous disease that is caused by autoantibodies to the dermoepidermal junction, mainly type VII collagen. Similarities in histology and immunopathology exist between BSLE and other primary bullous dermatoses, namely dermatitis herpetiformis DH and epidermolysis bullosa acquisita EBA , respectively.

However, clinical presentation combined with histology, immunological testing, and concomitant diagnosis of SLE distinguish this entity from other similar dermatoses. Diagnosis of this disease is important given its coexistence with SLE and its many complications. In addition, rituximab was recently found to be efficacious in recalcitrant cases of BSLE that do not respond to dapsone and immunosuppressants. We review the topic of BSLE with emphasis on clinical, histologic, and immunopathologic features, as well as new methods of diagnosis and treatment.

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Send even when there aren't any new results. Optional text in email:. Save Cancel. Create a file for external citation management software Create file Cancel. Full-text links Cite Favorites. Similar articles Bullous systemic lupus erythematosus. Sebaratnam DF, et al. Dermatol Clin. Epub Aug 3. PMID: Epidermolysis bullosa acquisita and bullous systemic lupus erythematosus. Diseases of autoimmunity to type VII collagen. Gammon WR, et al. PMID: Review.

Widespread vesiculobullous eruption in a year-old male. Acta Dermatovenerol Alp Pannonica Adriat. Bullous systemic lupus erythematosus with milia and calcinosis. Eckman JA, et al. Bullous SLE: a phenotypically distinctive but immunologically heterogeneous bullous disorder. J Invest Dermatol. Show more similar articles See all similar articles. Cited by 6 articles Vesiculobullous diseases in relation to lupus erythematosus. Rutnin S, Chanprapaph K. Rutnin S, et al.

Clin Cosmet Investig Dermatol. Bullous systemic lupus erythematosus - a case report. Autops Case Rep. Bullous systemic lupus erythematosus associated with increased activity of lupus nephritis: a case report and review of the literature.

Postepy Dermatol Alergol. Epub Aug No abstract available. Crusted lesions on the face of a child. Li YM, et al. Pediatr Dermatol. Bullous systemic lupus erythematosus in a year-old child. Hans-Bittner NR, et al. An Bras Dermatol. Show more "Cited by" articles See all "Cited by" articles.

Publication types Review Actions. Humans Actions. Substances Autoantibodies Actions. Immunoglobulin G Actions. Full-text links [x] Springer. Copy Download.

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Click here to learn What's New at our website. Shalin, M. Page views in 17, Cite this page: Grove N Bullous pemphigoid. Accessed June 5th, Common subepidermal, blistering, autoimmune disease of skin due to IgG antibodies to the hemidesmosomal antigens Bullous pemphigoid antigen 1 and 2 Patients present with tense bullae, which do not rupture easily, on an erythematous base. Essential features.

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