It is the result of a combination of innovative biochip technology and cutting edge research in molecular allergology. This advanced technology enables measurement of IgE antibodies to a fixed panel of components from 51 allergen sources in a single step, using only 30 ul of serum or plasma. ImmunoCAP ISAC is the first multiplex in vitro diagnostic tool for the allergy specialist that is based exclusively on allergen components. Thermo Scientific: Helping scientists meet the challenges they face in the lab or in the field every day. As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history. ImmunoCAP ISAC — When you need the bigger picture in allergy Trying to find the original cause for allergic reactions can sometimes feel like looking for a needle in a haystack.
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Shed light on the real sensitization profile of multisensitized patients. Reveal potential risk for severe food-related reactions. Identify the IgE antibody profile in patients with unsatisfactory response to treatment. Thanks to the cross-reacting proteins ImmunoCAP ISAC can give you information on hundreds of allergen sources in addition to the 51 sources the proteins are derived from. As a result, effective and optimized management can be started earlier, which in turn leads to improved patient health and quality of life.
Thermo Scientific: Helping scientists meet the challenges they face in the lab or in the field every day. As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history.
ImmunoCAP ISAC for tricky cases Most allergic patients have positive test results to numerous allergens and the true cause of symptoms can be difficult to identify due to an inconclusive medical history regarding the role of different allergens and reactions. All rights reserved. All trademarks are the property of Thermo Fisher Scientific Inc.
ImmunoCAP ISAC for tricky cases
The biochip technology takes the form of a miniaturised immunoassay platform where allergen components are immobilised in a microarray. The allergen components are spotted in triplets and covalently immobilised on a polymer coated slide. Each slide contains four microarrays giving results for four different samples per slide. Allergen-bound IgE antibodies are detected by a fluorescence labelled anti-IgE antibody. This educational website, provided by Thermo Fisher Scientific, ImmunoDiagnostics Division, has been produced in partnership with the Institute of Biomedical Science as a pioneering venture to promote excellence in laboratory practice using education and continuing professional development CPD resources.
ImmunoCAP ISAC for a range of sIgE antibody information
The information in this website is intended only for healthcare professionals. By entering this site, you are confirming that you are a healthcare professional. The information in this website is intended only for laboratory professionals. By entering this site, you are confirming that you are a laboratory professional. Capillary blood sampling can be used, thus enabling a less invasive procedure for testing young children. Purified natural or recombinant molecular allergen components are immobilized on a solid support biochip. This innovative test provides clinicians with a large amount of allergen specific IgE antibody information in one single step.