EPANUTIN INJECTION PDF

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Subscribe to Drugs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. We comply with the HONcode standard for trustworthy health information - verify here.

Author:Dozahn Docage
Country:Germany
Language:English (Spanish)
Genre:Sex
Published (Last):7 June 2018
Pages:330
PDF File Size:19.31 Mb
ePub File Size:8.42 Mb
ISBN:908-4-20414-973-5
Downloads:29524
Price:Free* [*Free Regsitration Required]
Uploader:Fenrim



Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.

Available for Android and iOS devices. Subscribe to Drugs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. We comply with the HONcode standard for trustworthy health information - verify here. Skip to Content. Epanutin RMP will be either injected into one of your large veins intravenously or into your muscle intramuscularly.

When given intravenously, Epanutin RMP must be diluted. The dose and concentration of the solution of Epanutin RMP you are given will be decided by your doctor and will be written as the equivalent dose of phenytoin sodium PE. The dose will be as mg per dose if given as an injection or mg per ml of solution if given as an infusion drip. Intravenous Epanutin is more reliably absorbed than oral Epanutin in very young babies.

If you think you have been given too much Epanutin RMP, contact your doctor immediately. If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse. Possible side effects Like all medicines, this medicine can cause side effects although not everybody gets them.

Tell your doctor immediately if you experience any of the following symptoms after being given this medicine. There is a higher incidence of this in black patients. In most cases this will improve on its own but in some cases it can be serious and require urgent medical treatment. If you develop potentially life-threatening skin rashes that causes blistering this can affect the mouth and tongue. These have been reported very rarely. If you notice bruising, fever, you are looking pale or you have a severe sore throat.

These may be the first signs of an abnormality of the blood, including decreases in the number of red blood cells, white cells or platelets. Your doctor may take regular blood samples to test for these effects.

Skin rash, fever, swollen glands, increase in a type of white blood cell eosinophilia , and inflammation of internal organs liver, lungs, heart, kidneys and large intestine , you may also experience pain and inflammation of the joints, these may be signs of a hypersensitivity reaction e. If you experience confusion or have a severe mental illness, as this may be a sign that you have high amounts of phenytoin in your blood.

On rare occassions, when the amount of the phenytoin in the blood remains high, irreversible brain injury N. This is not normally continued for longer than one week.

When switching back to oral Epanutin, the dose should be reduced to half the original oral dose for the same period of time that the intramuscular injection was given. This is because phenytoin continues to be released from your muscles for sometime after the injections have been given. If Epanutin does not stop your seizures, other treatments will be tried. Cardiac arrhythmias variations to normal heartbeat A dose of 3. This may be repeated a second time.

Older people Your doctor will not need to change your dose, but side effects may occur more often in older people. Children and adolescents No dosage adjustment is required, but children tend to breakdown the medicine faster than adults and this may mean that your doctor has to change the number or timing of the Epanutin doses. FPO 3. How Epanutin RMP is given Read all of this leaflet carefully before you are given this medicine because it contains important information for you.

You may need to read it again. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours. This includes any possible side effects not listed in this leaflet. See section 4. In this case, you will only be able to read this leaflet after you have had the product given to you.

Your doctor will have considered the important safety information in this leaflet, but your urgent need for treatment may have been more important than some of the normal cautions. Check them now, especially if you are going to continue to be given Epanutin RMP or any other form of phenytoin. Epanutin RMP is also used to control or prevent seizures for short periods of time when antiepileptic drugs cannot be taken by mouth.

Epanutin RMP can also be used to treat specific heart rhythm problems cardiac arrhythmias when these are caused by the drug digoxin, or when these do not respond well to treatment with other medicines, or when other treatments cannot be used.

You should consult your doctor if you are unsure why you have been given Epanutin RMP, if you do not feel better or if you feel worse. What is in this leaflet: 1. What Epanutin RMP is and what it is used for 2.

What you need to know before you are given Epanutin RMP 3. How Epanutin RMP is given 4. Possible side effects 5. How to store Epanutin RMP 6. Contents of the pack and other information 2. What you need to know before you are given Epanutin RMP 1.

What Epanutin RMP is and what it is used for This medicine is a solution for injection or infusion containing phenytoin, which belongs to a group of medicines called antiepileptic drugs. Epanutin RMP can be used to treat severe epileptic seizures or fits status epilepticus. Warnings and precautions Talk to your doctor, pharmacist or nurse before you are given Epanutin RMP if you suffer from or have suffered N. If you develop a rash or these skin symptoms, stop taking Epanutin, seek urgent advice from a doctor and tell him that you are taking this medicine.

Consult your doctor before discontinuing Epanutin. If you suddenly stop taking this medicine you may have a seizure. If you are taking phenytoin at the same time as you receive radiation therapy to your head and the dose of another medication called corticosteroids is reduced, you may more likely to develop a severe skin rash called erythema multiform or one that causes blistering called Stevens Johnson Syndrome or Toxic Epidermal Necrosis see Possible Side Effects in section 4.

Other medicines and Epanutin RMP Tell your doctor if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. A small number of people being treated with antiepileptics such as phenytoin sodium have had thoughts of harming or killing themselves.

If at any time you have these thoughts, immediately contact your doctor. Potentially life-threatening skin rashes Stevens Johnson syndrome, toxic epidermal necrolysis have been reported with the use of Epanutin, appearing initially as reddish target-like spots or circular patches often with central blisters on the trunk. Additional signs to look for include ulcers in the mouth, throat, nose, genitals and conjunctivitis red and swollen eyes.

These potentially life-threatening skin rashes are often accompanied by flu-like symptoms. The rash may progress to widespread blistering or peeling of the skin. The highest risk for occurrence of serious skin reactions is within the first weeks of treatment. Your doctor may need to test the amount of phenytoin in your blood to help decide if any of these drugs are affecting your treatment. Epanutin RMP may also interfere with certain laboratory tests that you may be given.

Epanutin RMP with drinking alcohol Drinking a lot of alcohol can also affect the concentration of phenytoin in your blood. Pregnancy and breast-feeding If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before you are given Epanutin.

You should not breast-feed if you are being given Epanutin RMP. Driving and using machines Epanutin RMP may cause dizziness or drowsiness. If you experience these symptoms, do not drive or use any tools or machinery and contact your doctor. Epanutin RMP contains ethanol and sodium This medicinal product contains 8. It may be harmful if you suffer from alcoholism.

It should be taken into account in pregnant or breast-feeding women, children and high risk groups such as patients with liver disease. This medicine contains up to 1. This should be considered if you are on a sodium-controlled diet. Your doctor may test your blood to see how much phenytoin is in the blood and may change your dose. Your blood pressure may also be lowered and experience heart problems when Epanutin is injected into your vein too quickly.

Check with your doctor or pharmacist if you are on long-term antiepileptic medication, have a history of osteoporosis, or take steroids. Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. You can also report side effects directly see details below.

By reporting side effects you can help provide more information on the safety of this medicine. United Kingdom Yellow Card Scheme website: www. The expiry date refers to the last day of that month. The pharmacist will also ensure that Epanutin RMP is kept in the original package. Epanutin RMP is for single use only. Any unused solution should be discarded immediately after initial use. Keep out of the sight and reach of children. The other ingredients are propylene glycol, ethanol alcohol , sodium hydroxide and water for injection.

Latest Drug Information Updates. Explore Apps. About About Drugs. All rights reserved.

CHRISTOPHER MCQUARRIE WOLVERINE SCRIPT PDF

GGC Medicines

Epanutin injection contains the active ingredient phenytoin, which is a type of medicine called an anticonvulsant. Phenytoin works by stabilising electrical activity in the brain. The brain and nerves are made up of many nerve cells that communicate with each other through electrical signals. These signals must be carefully regulated for the brain and nerves to function properly. When abnormally rapid and repetitive electrical signals are released in the brain, the brain becomes over-stimulated and normal function is disturbed.

LIBRO COMPLEMENTARIO ESCUELA SABATICA 2015 PDF

PHENYTOIN SODIUM PFIZER READY-MIXED PARENTERAL 250MG/5ML SOLUTION FOR INJECTION OR INFUSION

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Subscribe to Drugs.

DVAT 27A PDF

EPANUTIN READY-MIXED PARENTERAL 250MG/5ML SOLUTION FOR INJECTION OR INFUSION

Ensure ECG, blood pressure and respiratory function are monitored throughout the duration of the infusion. If phenytoin is already present but the patient is still not controlled, a 'top-up' loading dose may be useful. Table 2 gives the approximate increase in concentration following doses of —mg. The first dose should be given 12—24 hours after the loading dose. Oral or nasogastric administration should be used, whenever possible. Only use intravenous administration when these options are not feasible and where cardiac monitoring is available.

Related Articles